Jay Hou, PhD

Dr. Jay Hou received his B.S. in Physics and his M.S in Mechanical Engineering at the National Taiwan University, Taipei, Taiwan. Later he joined Dr. Robert Mauck’s Laboratory at the University of Pennsylvania and developed a high-throughput mechanical device to investigate the stiffness and diffusivity of tissue constructs. He received his PhD in 2018 from the Department of Mechanical Engineering at the Columbia University, advised by Dr. Gerard Atehsian. During his PhD, he developed a novel multiphasic and multiscale cell-tissue finite element computational model to study the mechanics, transport, and physiology of chondrocytes within cartilage.

Dr. Jay Hou’s postdoctoral training was conducted in Dr. David Odde’s Laboratory at the University of Minnesota. In his postdoc, he applied the biophysical modeling to study cancer cell migration under various conditions: with different adhesion sizes, on viscoelastic substrates, on substrates with stiffness gradients, and within 1D channels. He further applied the biophysical modeling, drug inhibition, bioinformatic analysis to explore the physical and molecular mechanisms of heterogeneous cell migration in glioblastoma PDX cells.

Dr. Jay Hou joined the faculty at Neurosurgery in 2024 and established the Brain Tumor Computational Laboratory, and his research goal is to establish computational and machine learning algorithms, along with experimental protocols, to study the tumor growth and diffusion in glioblastoma patients.

Degree
2004
B.S. Physics
National Taiwan University
Taipei, Taiwan

2007
M.S. Mechanical Engineering
National Taiwan University
Taipei, Taiwan

2018
Ph.D. Mechanical Engineering
Columbia University
New York, NY, USA

Fellowships
Postdoctoral Associate, Biomedical Engineering
University of Minnesota
Minneapolis, MN, USA

Titles
Research Scientist (PI), Neurosurgery Department
Director, Brain Tumor Computational Laboratory

Awards & Memberships
Dr. Hou has many honors, memberships and publications. Download his CV for a full record of credentials.